East Shinjuku Night High School has students with various challenges. Delinquent Taketo is trapped in a negative spiral. Filipina-Japanese Angela struggles with schoolwork, while Kasumi spends all her class hours in the infirmary. Shozo had to leave school to work in his youth. With guidance from their new science teacher, Fujitake, they work on an experiment for an academic conference.
The science club reunites and successfully registers for the conference on time. They are selected as one of the 15 schools to give a presentation, but Taketo and Kasumi struggle with their roles as presenters. Meanwhile, Fujitake receives an unexpected offer from Inose, leaving him puzzled. As Taketo senses something is off with his teacher, the day of the conference finally arrives.
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