In this new era, Catalina, now head of the DEA in Colombia, has a new challenge: to track down a criminal organization that is trafficking a new synthetic drug. What she ignores is that her daughter is part of the Cartel that traffics them and that Yésica, her worst enemy, is infiltrated in the DEA.
Santiago and Titi face off. Mariana's father wants to avenge his son. The new Mano Negra sends Yadith to watch over Mariana.
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