At the end of the 21st century, a rare disease called “Cagaster” broke out, turning humans into huge insects. Two-thirds of the earth‘s population was devoured by these insects before humanity made a decision: they must exterminate the infected people. In the year 2125 – thirty years after the discovery of Cagaster – at the edge of the desert close to the “cage” of the insects, a young pest exterminator named Kidou finds a man close to death due to the wounds by insects. The man entrusts his daughter Ilie to Kidou and asks him to search for the girl‘s mother…
As the battle between Salif’s forces and the defenders of E-05 come to an end, the survivors inside E-07's main tower confront their futures.
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